Solved My monitor goes to sleep when I launch this Steam game.

The GPU not getting enough power could cause such behaviour.

Some questions if I may;

Does every other game play without any issue.

What is the brand and model name or number of the PSU.

Is your 8GB of RAM a single stick or two 4GB sticks of 2666MHz or above capable.

See the below;

PREDALN316 said:

Wolf Quest: Anniversary Edition"

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Out of the games that you mention the above is the most demanding, see here

PREDALN316 said:

Sea Of Thieves,

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Next most demanding, see here

Pretty similar GPU requirements so you would expect to be able to play both games on the same settings, you may need to open a ticket on Steam about this as we cannot help you with anything under their control.

PREDALN316 said:

PSU: Cooler Master MWE White V2 500W

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Cooler Master do not make good PSUs and so much so that they are on the avoid list, in addition to the brand not being good, you should never use anything less than a Gold efficiency rated PSU from a proven brand when there is decent GPU present, an RX 480 8GB requires a PSU with a minimum of a 500W output and you will not get this from a CM PSU that is labelled as 500W, some claimed 500W CM PSUs can only actually produce 384W which is imo downright dangerous.

How old is the PSU that you have, better still if you can post a link so we can check the specs.

PREDALN316 said:

My 8GB of RAM is a single stick of 2666MHz

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Your RAM can only work in single channel mode at 1333MHz and this will cause you a bottleneck when the computer is under a full load.

Glad you got it sorted and thanks for sharing the solution so that it may help others

You are welcome